Tranexamic Acid

1. INCI & CAS

INCI: Tranexamic Acid · CAS: 1197-18-8

2. Role in the formula

Cosmetic guides often explore about 2–3% tranexamic acid in leave-on serums. This page does not claim a medicine, a injection use, or a guaranteed spot result.

3. Typical use levels (formulation guide)

• For serums, the reference gives 2–3% where the market allows in this reference.

Dissolve into water. Confirm the destination cosmetic listing before filing.

4. Regulatory sources & global compliance

• The CosIng record for Tranexamic Acid, where listed, is informational rather than product-specific authorization.
• The EU Cosmetics Regulation (EC) No 1223/2009 requires a safety assessment of the finished cosmetic containing Tranexamic Acid for the product in its final form.
• Review the documentation for the actual Tranexamic Acid grade and the filing requirements for the target market.

5. Safety & risk assessment

The use-level note is a reference for cosmetic formulation; it provides no evidence that a drug or OTC monograph applies and the completed cosmetic needs its own patch and stability checks.

6. Stability & packaging

Protect the sealed bulk from heat, sun, and unnecessary exposure; match the pack choice to the system's oxidation risk; test the selected package with the confirmed batch for stability and fit.

7. Claims language (Do / Don’t)

• The recorded cosmetic positioning for Tranexamic Acid highlights tranexamic-acid cosmetic.

• The development record does not demonstrate drug or therapeutic claims, clinical cures, or certification claims not confirmed for the product.
• This Tranexamic Acid listing should not be used to substantiate a whitening effect, acne treatment, perspiration control, sun protection, or hair growth.

1. INCI & CAS

INCI: Glycerin · CAS: 56-81-5

2. Role in the formula

The reference uses glycerin as a polyol humectant across washes, gels, and emulsions. Treat the percentage as development guidance.

3. Typical use levels (formulation guide)

• 3–8% is listed for gels and serums as a formulation guide.
• For creams, the reference gives 2–5% for the formula.
• For rinse-off, the reference gives 2–4% in this reference.

The water phase is the addition point for Glycerin; a separate melt is unnecessary.

4. Regulatory sources & global compliance

• A CosIng listing for Glycerin provides ingredient information, not approval of a supplied grade or finished product.
• Before EU placement, Regulation (EC) No 1223/2009 requires the final cosmetic with Glycerin to undergo a safety assessment as a finished-product assessment.
• Confirm the actual Glycerin grade from supplier documentation and check requirements where the product will be sold.

5. Safety & risk assessment

The guide records a level for cosmetic formulation purposes; it is not evidence of drug approval or OTC authorization with patch and stability testing still needed for the completed formula.

6. Stability & packaging

Protect the sealed bulk from heat, sun, and unnecessary exposure; if the formula is oxidation-sensitive, an airless or pump format may be considered; confirm compatibility and stability using the selected formula and pack.

7. Claims language (Do / Don’t)

• For cosmetic use, this entry records Glycerin in a direction centered on humectant function.

• The cosmetic listing does not substantiate drug effects, clinical cures, or unsupported product certifications.
• The information about Glycerin does not confirm whitening, acne treatment, antiperspirant effects, sunscreen use, or hair growth.

1. INCI & CAS

INCI: Squalane · CAS: 111-01-3

2. Role in the formula

Squalane provides the referenced hydrocarbon-emollient role in a plant-derived grade; mineral oil is not part of this guide.

3. Typical use levels (formulation guide)

• Formulation guidance for gel-creams: 2–6% for the formula.
• The dry oils use-level reference is 10–30% as a formulation guide.
• Formulation guidance for balms: 5–15% in this reference.

Add Squalane to the oil phase; no high-shear wax step is required.

4. Regulatory sources & global compliance

• A CosIng listing for Squalane provides ingredient information, not approval of a supplied grade or finished product.
• Regulation (EC) No 1223/2009 requires the final cosmetic with Squalane to undergo a safety assessment at the level of the finished cosmetic product.
• Confirm the received Squalane grade against supplier documentation, then verify the intended market's filing requirements.

5. Safety & risk assessment

The use-level note is a reference for cosmetic formulation; it should not be read as a drug authorization or OTC listing and patch and stability testing remain part of finished-product review.

6. Stability & packaging

For bulk storage, avoid warmth and direct sun and keep the container closed; review airless or pump options if oxidation presents a concern; assess the confirmed formula for stability and package compatibility.

7. Claims language (Do / Don’t)

• The cosmetic role of Squalane is presented as a light-emollient role.

• This formulation entry cannot substantiate drug or therapeutic claims, clinical cures, or certification claims not confirmed for the product.
• The ingredient record for Squalane does not confirm whitening, acne treatment, antiperspirant effects, sunscreen use, or hair growth.