Ceramide Complex

1. INCI & CAS

INCI: Ceramide NP · CAS: 100403-19-8

2. Role in the formula

Ceramide NP is the primary sphingolipid in a multi-ceramide guide. It is paired here with cholesterol as a lamellar co-lipid. Levels are guides, not a skin-identical drug claim.

3. Typical use levels (formulation guide)

• Formulation guidance for gel-creams: 0.1–0.3% as a formulation guide.
• For richer creams, use 0.2–0.5% in this reference.

Introduce from a pre-dispersed lipid concentrate or a warm oil phase. Avoid long holds at high heat after the lipids melt.

4. Regulatory sources & global compliance

• CosIng provides reference information for Ceramide NP; confirm the specific grade and intended use against market requirements.
• For a cosmetic sold in the EU, Regulation (EC) No 1223/2009 requires a safety review of the finished cosmetic in which Ceramide NP is used for the complete formula intended for sale.
• Compare the received Ceramide NP material with its supplier specification and review destination-market filing needs.

5. Safety & risk assessment

Treat the listed amount as cosmetic-development guidance; this reference is not approval for drug use or OTC marketing and the completed cosmetic needs its own patch and stability checks.

6. Stability & packaging

Protect sealed bulk from warmth and direct light; match the pack choice to the system's oxidation risk; confirm compatibility and stability using the selected formula and pack.

7. Claims language (Do / Don’t)

• The listed cosmetic direction for Ceramide NP emphasizes ceramide barrier-lipid.

• This cosmetic guide does not establish drug claims, cure claims, or a certification that is absent from the product records.
• The Ceramide NP entry does not establish whitening effects, acne treatment, antiperspirant performance, sunscreen protection, or hair growth.

1. INCI & CAS

INCI: Cholesterol · CAS: 57-88-5

2. Role in the formula

Cholesterol is the sterol co-lipid used with ceramides in barrier emulsions. This is a cosmetic lipid, not a serum-cholesterol claim.

3. Typical use levels (formulation guide)

• The gel-creams use-level reference is 0.1–0.3% for the formula.
• For richer creams, use 0.2–0.5% as a formulation guide.

Melt with the ceramide phase and cool under controlled shear.

4. Regulatory sources & global compliance

• CosIng provides reference information for Cholesterol; confirm the specific grade and intended use against market requirements.
• Before EU placement, Regulation (EC) No 1223/2009 requires a safety assessment covering the complete formulation with Cholesterol before release of the finished cosmetic.
• Establish grade-specific details for Cholesterol from the supplier and assess filing requirements in the intended market.

5. Safety & risk assessment

The listed use rate is intended as a cosmetic-development guide; it should not be read as a drug authorization or OTC listing with patch response and finished-product stability still to be verified.

6. Stability & packaging

For bulk storage, avoid warmth and direct sun and keep the container closed; choose a package with oxidation sensitivity in view; test the selected package with the confirmed batch for stability and fit.

7. Claims language (Do / Don’t)

• This guide frames Cholesterol's cosmetic direction around lamellar co-lipid.

• This formulation entry does not substantiate drug-treatment outcomes, clinical cures, or certifications not documented for the SKU.
• This reference for Cholesterol should not be cited in support of whitening effects, acne treatment, antiperspirant performance, sunscreen protection, or hair growth.

1. INCI & CAS

INCI: Glycerin · CAS: 56-81-5

2. Role in the formula

The listed glycerin role is that of a polyol humectant in cosmetic washes, gels, and emulsions; the amount is guidance only.

3. Typical use levels (formulation guide)

• Formulation guidance for gels and serums: 3–8% as a formulation guide.
• The guide range for creams is 2–5% in this reference.
• Formulation guidance for rinse-off: 2–4%.

Add Glycerin in the water phase without melting it first.

4. Regulatory sources & global compliance

• The CosIng record for Glycerin, where listed, is informational rather than product-specific authorization.
• The framework in Regulation (EC) No 1223/2009 requires the completed product containing Glycerin to receive its own safety assessment as part of the finished cosmetic's safety documentation.
• Establish grade-specific details for Glycerin from the supplier and assess filing requirements in the intended market.

5. Safety & risk assessment

This level is a cosmetic-formulation guide; this reference is not approval for drug use or OTC marketing and patch and stability testing remain part of finished-product review.

6. Stability & packaging

Keep the bulk container closed and shaded in a cool area; select packaging with the formula's oxidation sensitivity in mind; check the finished batch's stability and package compatibility.

7. Claims language (Do / Don’t)

• The cosmetic formulation concept for Glycerin centers on humectant function.

• The ingredient guidance cannot substantiate drug effects, cures, or certification claims that go beyond the documented ingredient information.
• The ingredient note for Glycerin offers no support for whitening, acne treatment, antiperspirant effects, sunscreen use, or hair growth.