Panthenol

1. INCI & CAS

INCI: Panthenol · CAS: 81-13-0

2. Role in the formula

The reference describes D-panthenol as a water-soluble humectant for serums, gels, lotions, and washes. Its level is not a batch test result.

3. Typical use levels (formulation guide)

• Formulation guidance for serums and gels: 1–5% for the formula.
• The formulation record indicates 1–3% for creams and lotions.
• The rinse-off washes use-level reference is 0.5–2% in this reference.

Water solubility and cool-down addition are specified for Panthenol; typical leave-on pH is about 5–6.

4. Regulatory sources & global compliance

• CosIng may identify Panthenol as an ingredient, but its entry does not approve a material grade or finished formula.
• The EU Cosmetics Regulation (EC) No 1223/2009 requires the finished product's safety, including the formula in which Panthenol is used, to be assessed as part of the finished cosmetic's safety documentation.
• Review the documentation for the actual Panthenol grade and the filing requirements for the target market.

5. Safety & risk assessment

The stated concentration is a cosmetic-development reference; it is not evidence of drug approval or OTC authorization so the finished cosmetic should receive patch and stability checks.

6. Stability & packaging

Store the bulk in a closed container in a cool, shaded place; select packaging with the formula's oxidation sensitivity in mind; follow with stability and packaging checks on the confirmed batch.

7. Claims language (Do / Don’t)

• The cosmetic concept for Panthenol in this entry centers on comfort and humectant support.

• The available ingredient details does not demonstrate drug or therapeutic claims, clinical cures, or certification claims not confirmed for the product.
• The Panthenol entry should not be used to substantiate whitening, acne treatment, antiperspirant effects, sunscreen use, or hair growth.

1. INCI & CAS

INCI: Allantoin · CAS: 97-59-6

2. Role in the formula

Allantoin is used around 0.1–0.5% in cosmetic leave-ons. This bulk listing does not by itself make an OTC skin-protectant claim.

3. Typical use levels (formulation guide)

• 0.1–0.5% is listed for creams, gels and washes for the formula.

For dissolution, use warm water. It recrystallises if the level is too high for the solvent.

4. Regulatory sources & global compliance

• If Allantoin appears in CosIng, its entry is informational and does not approve a specific grade or finished cosmetic.
• An EU-market cosmetic under Regulation (EC) No 1223/2009 requires the completed product containing Allantoin to receive its own safety assessment in the final product context.
• Review the supplier TDS for the received Allantoin grade, together with the target market's current filing requirements.

5. Safety & risk assessment

The concentration shown is guidance for cosmetic formulation; it is not evidence of drug approval or OTC authorization with patch assessment and finished-formula stability testing still required.

6. Stability & packaging

Protect the sealed bulk from heat, sun, and unnecessary exposure; review airless or pump options if oxidation presents a concern; confirm final stability and pack compatibility on a representative batch.

7. Claims language (Do / Don’t)

• The cosmetic formulation concept for Allantoin centers on low-dose allantoin.

• This reference does not substantiate drug effects, clinical cures, or unsupported product certifications.
• The documented facts for Allantoin does not substantiate whitening, acne treatment, antiperspirant effects, sunscreen use, or hair growth.

1. INCI & CAS

INCI: Glycerin · CAS: 56-81-5

2. Role in the formula

For emulsions, gels, and washes, this guide assigns glycerin a polyol-humectant role. Its level is not a batch assay.

3. Typical use levels (formulation guide)

• The level shown for gels and serums is 3–8%.
• For creams, use 2–5% in this reference.
• The guide range for rinse-off is 2–4% as a formulation guide.

The water phase is the addition point for Glycerin; a separate melt is unnecessary.

4. Regulatory sources & global compliance

• Use CosIng's information on Glycerin as a reference, then verify the specific grade and intended use under market rules.
• Before EU placement, Regulation (EC) No 1223/2009 requires a safety evaluation of the product containing Glycerin as it will be marketed before release of the finished cosmetic.
• Review the supplier TDS for the received Glycerin grade, together with the target market's current filing requirements.

5. Safety & risk assessment

The stated concentration is a cosmetic-development reference; it does not establish drug approval or OTC-monograph status with patch response and finished-product stability still to be verified.

6. Stability & packaging

Keep the ingredient in cool, closed bulk storage away from sunlight; take oxidation sensitivity into account when selecting the final pack; check the final package and formula together for compatibility and stability.

7. Claims language (Do / Don’t)

• The formulation note describes Glycerin as part of a cosmetic direction focused on humectant function.

• The development record does not support drug or therapeutic claims, clinical cures, or certification claims not confirmed for the product.
• This cosmetic entry naming Glycerin should not be used to substantiate whitening, treatment of acne, perspiration control, sun protection, or hair growth.