Niacinamide Tone Care Serum Base

1. INCI & CAS

INCI: Niacinamide · CAS: 98-92-0

2. Role in the formula

Niacinamide is widely used in leave-on cosmetic guides around 2–5%. This is not a drug monograph claim and not a whitening drug claim.

3. Typical use levels (formulation guide)

• The guide range for serums is 2–5% for the formula.
• Gel-creams: 2–4% as a formulation guide.
• The formulation record indicates 2–3% for toners.

Dissolve in the water phase. Keep finished pH roughly 5–6.5 so it stays in the cosmetic range used by formulators.

4. Regulatory sources & global compliance

• If CosIng lists Niacinamide, that listing remains ingredient information; check rules for the intended market and use.
• An EU-market cosmetic under Regulation (EC) No 1223/2009 requires a safety assessment of the complete cosmetic formula containing Niacinamide rather than for an ingredient name alone.
• Verify the purchased Niacinamide grade using supplier data, alongside the applicable filing rules for the destination market.

5. Safety & risk assessment

This formulation note gives a cosmetic-use reference level; it makes no claim of drug or OTC authorization while finished-product patch and stability testing remain necessary.

6. Stability & packaging

Keep bulk supplies closed, cool, and protected from sunlight; where appropriate, assess an airless or pump pack for oxidation-sensitive systems; verify the chosen pack against the tested formula.

7. Claims language (Do / Don’t)

• The recorded cosmetic positioning for Niacinamide highlights niacinamide conditioning.

• The ingredient record is not evidence of a drug effect, a clinical cure, or certification status not established for the SKU.
• This reference for Niacinamide cannot verify skin whitening, treatment of acne, sweat control, UV protection, or hair-growth results.

1. INCI & CAS

INCI: Glycerin · CAS: 56-81-5

2. Role in the formula

The glycerin note covers its polyol-humectant role in washes, gels, and emulsions and gives a formulation guide level.

3. Typical use levels (formulation guide)

• For gels and serums, the reference gives 3–8%.
• Creams: 2–5% as a formulation guide.
• For rinse-off, the reference gives 2–4% in this reference.

Add Glycerin to the water phase; no separate melt step is needed.

4. Regulatory sources & global compliance

• CosIng information about Glycerin does not itself authorize a particular grade or finished cosmetic.
• The finished-product provisions of Regulation (EC) No 1223/2009 require a safety evaluation of the product containing Glycerin as it will be marketed at the level of the finished cosmetic product.
• Confirm the received Glycerin grade against supplier documentation, then verify the intended market's filing requirements.

5. Safety & risk assessment

This entry provides guidance for cosmetic use only; the listed level does not itself confer drug or OTC status and the finished formula still needs patch and stability testing.

6. Stability & packaging

Use cool, sealed storage away from strong light for the bulk; evaluate packaging against the formula's susceptibility to oxidation; test the selected package with the confirmed batch for stability and fit.

7. Claims language (Do / Don’t)

• This guide frames Glycerin's cosmetic direction around humectant function.

• This formulation entry cannot verify therapeutic effects, curative outcomes, or unsupported certification statements.
• The ingredient note for Glycerin should not be used to substantiate a whitening effect, acne treatment, perspiration control, sun protection, or hair growth.

1. INCI & CAS

INCI: Propanediol · CAS: 504-63-2

2. Role in the formula

Use the identity 1,3-propanediol for the listed humectant/solvent role. The guide does not call for propylene glycol.

3. Typical use levels (formulation guide)

• The most water chassis use-level reference is 2–8% as a formulation guide.

Incorporate Propanediol in the water phase.

4. Regulatory sources & global compliance

• If Propanediol appears in CosIng, its entry is informational and does not approve a specific grade or finished cosmetic.
• Regulation (EC) No 1223/2009 requires a safety assessment of the complete cosmetic formula containing Propanediol as a finished-product assessment.
• Use current supplier documentation for the purchased Propanediol grade and verify applicable destination-market filings.

5. Safety & risk assessment

The stated concentration is a cosmetic-development reference; it makes no claim of drug or OTC authorization and the completed formula still requires stability and patch testing.

6. Stability & packaging

Store sealed bulk away from heat and sunlight; evaluate packaging against the formula's susceptibility to oxidation; follow with stability and packaging checks on the confirmed batch.

7. Claims language (Do / Don’t)

• The listed cosmetic direction for Propanediol emphasizes propanediol solvent.

• This cosmetic guide does not establish drug claims, cure claims, or a certification that is absent from the product records.
• This reference for Propanediol does not confirm a whitening result, acne-treatment effect, antiperspirant use, sunscreen performance, or hair growth.