Ceramide Comfort Cream Base

1. INCI & CAS

INCI: Ceramide NP · CAS: 100403-19-8

2. Role in the formula

Ceramide NP is the primary sphingolipid in a multi-ceramide guide. It is paired here with cholesterol as a lamellar co-lipid. Levels are guides, not a skin-identical drug claim.

3. Typical use levels (formulation guide)

• The gel-creams use-level reference is 0.1–0.3% in this reference.
• Formulation guidance for richer creams: 0.2–0.5% as a formulation guide.

Introduce from a pre-dispersed lipid concentrate or a warm oil phase. Avoid long holds at high heat after the lipids melt.

4. Regulatory sources & global compliance

• CosIng provides reference information for Ceramide NP; confirm the specific grade and intended use against market requirements.
• The EU Cosmetics Regulation (EC) No 1223/2009 requires a product-level safety assessment for the complete formula that contains Ceramide NP for the product in its final form.
• Compare the received Ceramide NP material with its supplier specification and review destination-market filing needs.

5. Safety & risk assessment

The stated concentration is a cosmetic-development reference; it makes no claim of drug or OTC authorization with patch assessment and finished-formula stability testing still required.

6. Stability & packaging

Protect the sealed bulk from heat, sun, and unnecessary exposure; choose a package with oxidation sensitivity in view; use batch testing to verify stability and package compatibility.

7. Claims language (Do / Don’t)

• The cosmetic concept for Ceramide NP in this entry centers on ceramide barrier-lipid.

• The development record cannot substantiate claims of drug activity, a clinical cure, or an undocumented product certification.
• This reference for Ceramide NP cannot verify whitening effects, acne treatment, antiperspirant performance, sunscreen protection, or hair growth.

1. INCI & CAS

INCI: Cholesterol · CAS: 57-88-5

2. Role in the formula

Cholesterol is the sterol co-lipid used with ceramides in barrier emulsions. This is a cosmetic lipid, not a serum-cholesterol claim.

3. Typical use levels (formulation guide)

• The stated reference for gel-creams is 0.1–0.3% for the formula.
• The guide range for richer creams is 0.2–0.5% in this reference.

Melt with the ceramide phase and cool under controlled shear.

4. Regulatory sources & global compliance

• If Cholesterol appears in CosIng, its entry is informational and does not approve a specific grade or finished cosmetic.
• The EU Cosmetics Regulation (EC) No 1223/2009 requires the final cosmetic with Cholesterol to undergo a safety assessment for the specific product as it will be marketed.
• Review the documentation for the actual Cholesterol grade and the filing requirements for the target market.

5. Safety & risk assessment

Read the recorded level as a cosmetic formulation guide; it is not evidence of drug approval or OTC authorization and the completed cosmetic needs its own patch and stability checks.

6. Stability & packaging

Protect the sealed bulk from heat, sun, and unnecessary exposure; if the formula is oxidation-sensitive, an airless or pump format may be considered; test the selected package with the confirmed batch for stability and fit.

7. Claims language (Do / Don’t)

• The recorded cosmetic positioning for Cholesterol highlights lamellar co-lipid.

• The ingredient guidance cannot substantiate therapeutic results, cure claims, or unverified certification claims.
• The ingredient record for Cholesterol is not evidence for skin whitening, acne care, sweat reduction, sun protection, or hair-growth outcomes.

1. INCI & CAS

INCI: Glycerin · CAS: 56-81-5

2. Role in the formula

As a polyol humectant, glycerin is used in cosmetic emulsions, gels, and washes. The recorded percentage is not a measured batch value.

3. Typical use levels (formulation guide)

• The level shown for gels and serums is 3–8% for the formula.
• The guide range for creams is 2–5% in this reference.
• 2–4% is listed for rinse-off for the formula.

Incorporate Glycerin in the water phase without a separate melt step.

4. Regulatory sources & global compliance

• Treat any CosIng entry for Glycerin as a reference only; verify the grade and intended use under current market rules.
• An EU-market cosmetic under Regulation (EC) No 1223/2009 requires a safety assessment of the complete cosmetic formula containing Glycerin for the completed formula, not simply for an ingredient in isolation.
• Use the supplier TDS to confirm grade-specific details for Glycerin and review the destination market's requirements.

5. Safety & risk assessment

The guide records a level for cosmetic formulation purposes; it does not qualify a finished product as a drug or OTC product and the completed cosmetic needs its own patch and stability checks.

6. Stability & packaging

Maintain cool, closed, light-protected storage for the bulk material; if the formula is oxidation-sensitive, an airless or pump format may be considered; verify the chosen pack against the tested formula.

7. Claims language (Do / Don’t)

• The formulation note describes Glycerin as part of a cosmetic direction focused on humectant function.

• This ingredient reference does not establish therapeutic effects, curative outcomes, or unsupported certification statements.
• The documented facts for Glycerin cannot verify whitening, acne-treatment, antiperspirant, sun-protection, or hair-growth benefits.